1985

Hájek, I., Teisinger, J.,Syková, E. (1985) The effect of opioids and of naloxone on Na+/K+ - adenosinetriphosphatase activity in frog spinal cord membrane fractions. Neurosci. Lett. 59: 291-295. Abstract

Syková, E., Hájek, I., Chvátal,A., Kriz, N., Diatchkova, G.I. (1985) Changes in extracellular potassium accumulation produced by opioids and naloxone in frog spinal cord: relation to changes of Na-K pump activity. Neurosci. Lett. 59: 285-290. Abstract . PDF file (250 k)

Syková, E., Kriz, N., Hájek, I. (1985) Role of endogenous opiates and extracellular K+ accumulation in the inhibition of frog spinal reflexes by electrical skin stimulation. Physiol. Bohemoslov. 34: 548-561. Abstract

1986

1987

Syková, E., Syka, J., Johnstone,B.M., Yates, G.K. (1987) Longitudinal flow of endolymph measured by distribution of tetraethylammonium and choline in scala media. Hearing Res. 28: 161-171. Abstract

Syková, E. (1987) Modulation of spinal cord transmission by changes in extracellular K+ activity and extracellular volume. Can. J. Physiol. Pharmacol. 65: 1058-1066. Abstract

1988

Svoboda, J., Motin, V.G., Hájek, I., Syková, E. (1988) Increase in extracellular potassium level in rat spinal dorsal horn induced by noxious stimulation and peripheral injury. Brain Res. 458: 97-105. Abstract

Syková, E., Orkand, R.K.,Chvátal, A., Hájek, I., Kriz, N. (1988) Effect of carbon dioxide on extracellular potassium accumulation and volume in isolated frog spinal cord. Pflügers Arch. 412: 183-187. Abstract . PDF file (416 k)

Syková, E., Svoboda, J., Chvátal,A., Jendelová, P. (1988) Extracellular pH and stimulated neurons. Ciba Found Symp. 139:220-35. Abstract . PDF file (688 k)

1989

Syková, E. (1989) Activity-related extracellular pH transients in spinal cord. Verh. Dtsch. Zool. Ges. 82:153-163. PDF file (699 k)

Astion, M.L., Chvátal, A.,Orkand, R.K. (1989) Na+/H+ exchange in glial cells of Necturus optic nerve, Neurosci. Lett., 107:167-172. Abstract . PDF file (290 k)

1990

Sykova, E. and Svoboda, J.(1990) Extracellular alkaline-acid-alkaline transients in the rat spinal cord evoked by peripheral stimulation. Brain Res. 512: 181-189. Abstract 

1991

Svoboda, J. and Sykova,E.(1991) Extracellular space volume changes in the rat spinal cord produced by nerve stimulation and peripheral injury. Brain Res. 560: 216-224. Abstract

Sykova, E. (1991) Ionic and volume changes in neuronal microenvironment. Physiol. Res. 40: 213-222.

Astion, M.L., Chvatal, A. and Orkand, R.K. (1991) Further studies of electrogenic Na+/HCO3- cotransport in glial cells of Necturus optic nerve: Regulation of pHi, Glia, 4:461-468. Abstract . PDF file (720 k)

Chvatal, A. and Kettenmann, H. (1991) Effect of steroids on gamma-aminobutyrate-induced currents in cultured rat astrocytes, Pflügers Arch., 419:263-266. Abstract . PDF file (331 k)

Hoppe, D., Chvátal, A., Orkand,R.K., Ransom, B.R. and Kettenmann, H. (1991) Characteristics of activity-dependent potassium accumulation in mammalian peripheral nerve, Brain Res., 552:106-112.Abstract . PDF file (573 k) 

1992

Ng, K.T., Gibbs, M.E., Crowe, S.F., Sedman, G.L., Hua, F., Zhao, W., O´Dowd, B., Rickard, N., Gibbs, C.L., Sykova, E., Svoboda, J. and Jendelova., P. (1991) Molecular mechanisms of memory formation. Mol. Neurobiol. 5: 333-350. Abstract

Ng, K.T., Gibbs, M.E., Gibbs, C.L., Sedman, G., Sykova, E., Svoboda, J., Jendelova, P., O´Dowd, B.O., Rickard, N. and Crowe, S.F. (1992) Ion involvement in memory formation: The potential role of astrocytes. Prog. Brain Res. 94:104-118. PDF file (844 k)

Sykova, E. (1992) Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells. Berlin, Heidelberg, New York: Springer-Verlag. pages 1-167.

Sykova, E., Jendelova, P., Svoboda, J. and Chvatal, A. (1992) Extracellular K+, pH and volume changes in spinal cord of adult rats and during postnatal development. Can. J.Physiol. Pharmacol. 70: S301-S309. Abstract . PDF file (930 k)

Sykova, E., Jendelova, P., Simonova, Z. and Chvatal, A. (1992) K+ and pH homeostasis in the developing rat spinal cord is impaired by early postnatal X-irradiation. Brain Res.594: 19-30. Abstract . PDF file (5.7 M)

Sykova, E., Svoboda, J., Simonova, Z. and Jendelova, P. (1992) Role of astrocytes in ionic and volume homeostasis in spinal cord during development and injury. Prog. Brain Res.94:47-56. PDF file (642 k) 

1993

Sykova, E. and Chvatal,A.(1993) Extracellular ionic and volume changes: The role in glia-neuron interaction. J. Chem. Neuroanatom. 6: 247-260. Abstract . PDF file (1.2 M)

Sykova, E., Chvatal, A., Jendelova, P. Svoboda, J. (1993) Activity-related changes in extracellular pH, K+ and volume: Role of glia in ion homeostasis in spinal cord. In: Functions of Neuroglia. Eds. A.I. Roitbak, E.V. Ocherashvili, Moscow: Kabur, pages 59-65. PDF file (330 k)

Sykova, E., Svoboda, J., Chvatal. A., Polak, J. (1993) Ionic and volume changes in CNS during stimulation, injury, postnatal development and anoxia. In: Migraine-Basic Mechanisms and Treatment. Eds. A. Lehmenkühler, K.H. Grotemeyer, F. Tegmeier. München: Urban and Schwarzenberg, pages 491-510. PDF file (820 k) 

1994

Sykova, E., Svoboda, J., Polak, J. and Chvatal, A. (1994) Extracellular volume fraction and diffusion characteristics during progressive ischemia and terminal anoxia in the spinal cord of the rat. J. Cereb. Blood Flow Metab. 14: 301-311. Abstract . PDF file (940 k) 

1995

Pastor, A., Chvatal, A., Sykova,E., and Kettenmann, H. (1995) Glycine- and GABA- activated currents in identified glial cells of the developing rat spinal cord slice. Eur. J. Neurosci. 7:1188-1198. Abstract . PDF file (3.3 M)

Sykova, E. (1995) Glie a mikroprostredi bunek v CNS. V: Pokroky v neurovedach. (Skripta pro vyuku neuroved.) 109-135. PDF file (1.6 M) 

1996

Simonova, Z., Svoboda, J., Orkand, P., Bernard, C.C.A., Lassmann, H. and Sykova, E. (1996) Changesof extracellular space volume and tortuosity in the spinal cord of Lewis rats with experimental autoimmune encephalomyelitis. Physiol. Res., 45,11-22. Abstract . PDF file (2.9 M)

Van Der Toorn, A., Sykova, E., Dijkhuizen, R.M., Vorisek. I., Vargova, L., Skobisova, E., Van Lookeren Campagne, M., Reese, T. and Nicolay, K. (1996) Dynamic changes in water ADC, energy metabolism, extracellular space volume, and tortuosity in neonatal rat brain during global ischemia. Magn. Res. Med., 36:52-60. Abstract . PDF file (1.2 M)

Hertz, L., Gibbs, M.E.,O´Dowd, B.S., Ng, K.T., Sedman, G.L., Peng, L., Hajek, I., Pow, D.V., Robinson,S.R. and Sykova, E. (1996) Astrocyte-neuron interaction in memory processing in neonate chick. Neurosci. Biobehav. Rev. 20:537-551. Abstract . PDF file (4.5 M)

Sykova, E., Chvatal, A., Vargova, L., Vorisek, I. (1996) Extracellular space ionic composition, volume and geometry during neuronal activity and pathological states. In: Intracranial and Intralabyrinthine Fluids - Basic Aspects and Clinical Applications, eds. A. Ernst, R. Marchbanks, M. Samii. Berlin: Springer Verlag, pages 9-22. PDF file (780 k) 

1997

Sykova, E. (1997) The extracellular space in the CNS: Its regulation, volume and geometry in normal and pathological neuronal function. The Neuroscientist, 3: 28-41. PDF file (3 M)

Vorisek, I. and Sykova,E.(1997) Ischemia-induced changes in the extracellular space diffusion parameters, K+ and pH in the developing rat cortex and corpus callosum. J. Cereb. Blood Flow Metab., 17: 191-203. Abstract . PDF file (1.3 M)

Chvatal, A., Berger, T., Vorisek,I., Orkand, R. K., Kettenmann H. and Sykova E. (1997) Changes in glial K+ currents with decreased extracellular volume in developing rat white matter. J. Neurosci. Res. 49: 98-106. Abstract . PDF file (141 k)

Harvey, A. R., Kendall,C.L.and Sykova, E. (1997) The status and organization of astrocytes, oligodendroglia and microglia in grafts of fetal rat cerebral cortex. Neurosci. Lett. 228: 58-62. Abstract . PDF file (692 k)

Vorisek, I. and Sykova,E.(1997) Evolution of anisotropic diffusion in the developing rat corpus callosum. J. Neurophysiol. 78: 912-919. Abstract . PDF file (679 k)

Prokopova, S., Vargova,L.and Sykova, E. (1997) Heterogeneous and anisotropic diffusion in the developing rat spinal cord. NeuroReport 8: 3527-3532. Abstract . PDF file (1.2 M) 

1998

Mazel, T, Simonová, Z. and Sykova, E. (1998) Diffusion heterogeneity and anisotropy in rat hippocampus. Neuroreport 9: 1299-1304. Abstract . PDF file (1.7 M)

Woerly, S., Pinet, E., De Robertis, L., Bousmina, M., Laroche, G., Roitbak, T., Vargova, L. and Sykova, E. (1998) Heterogeneous PHPMA hydrogels for tissue repair and axonal regeneration in the injured spinal cord. J. Biomat. Sci. Polymer Edn. 9:681-711. Abstract . PDF file (5.9 M)

Ziak, D., Chvatal, A. and Sykova, E. (1998) Glutamate, kainate and N-methyl-D-aspartate - evoked membrane currents in identified glial cells in the rat spinal cord slice. Physiol.Res. 47: 365-375. Abstract . PDF file (825 k)

Anderova, M., Duchene, A.D.,Barbara, J.-G., Takeda, K. (1998) Vasoactive intestinal peptide potentiates and directly stimulates catecholamine secretion from rat adrenal chromaffin cells. Brain Res. 809: 97-106. Abstract . PDF file (406 k)

Sykova, E., Mazel, T., Simonova, Z. (1998) Diffusion constraints and neuron-glia interaction during aging. Exp. Gerontology 33:837-851. Abstract . PDF file(427 k)

Pfeuffer, J., Dreher, W., Sykova, E., Leibfritz, D. (1998) Water signal attenuation in diffusion-weighted ¹HNMR experiments during cerebral ischemia: Influence of intracellular restrictions, extracellular tortuosity, and exchange. Magn. Reson. Imaging 16:1023-1032.Abstract . PDF file (186 k) 

1999

Sykova, E., Roitbak, T., Mazel,T., Simonová, Z. Harvey, A.R. (1999) Astrocytes,oligodendroglia, extracellular space volume and geometry in rat fetal brain grafts. Neuroscience. 91:783-98. Abstract .PDF file (2.4 M)

Jansson, A., Mazel, T., Andbjer, B., Rosén, L., Guidolin, D., Zoli, M., Syková, E., Agnati, L. Fuxe, K.(1999) Effects of nitric oxide inhibition on the spread of biotinylated dextran and on extracellular space parameters in the neostriatum of the male rat. Neuroscience 91:69-80. Abstract . PDF file (1.1 M)

Chvatal, A., Anderova, M., Ziak, D., Sykova, E. (1999) Glial depolarization evokes a larger potassium accumulation around oligodendrocytes than around astrocytes in gray matter of rat spinal cord slices. J. Neurosci. Res. 56:493-505. Abstract . PDF file (293 k)

Zoli, M., Jansson, A., Sykova, E., Agnati, L.F., Fuxe, K. (1999) Intercellular communication in the central nervous system. The emergence of the volume transmission concept and its relevance for neuropsychopharmacology. Trends. Pharmacol. Sci. 20:142-50. Abstract . PDF file (240 k)

Roitbak, T., Sykova, E. (1999) Diffusion barriers evoked in the rat cortex  by reactive astrogliosis. Glia 28: 40-48. Abstract . PDF file (632 k)

Woerly, S., Petrov, P., Sykova, E., Roitbak, T., Simonova, Z., Harvey, A.R. (1999) Neural tissue formation within porous hydrogels implanted in brain and spinal cord lesions: Ultrastructural, immunohistochemical, and diffusion studies. Tissue Eng. 5: 467-488. Abstract . PDF file (7.8 M)

Chvatal, A., Sykova, E. (1999) Membranove vlastnosti gliovych bunek v centralnim nervovem systemu. Psychiatrie, Suppl 2: 41-47. Abstract (in english) .  PDF file (4.6 M - in czech) 

2000

Sykova, E., Chvátal, A. (2000) Glial cells and volume transmission in the CNS. Neurochem. Int. 36: 397-409. Abstract .PDF file (642 k)

Chvatal, A. and Sykova, E.(2000) Glial influence on neuronal signaling. Prog. Brain. Res. 125: 199-216. PDF file (1.7 M)

Sykova, E., Mazel, T., Vargova,L., Vorisek, I. and Prokopova, S., (2000) Extracellular space diffusion and pathological states. Prog. Brain. Res. 125: 155-178. PDF file (4.4 M)

Jansson, A., Lippoldt, A., Mazel, T, Bartfai, T., Ogren, S.-O., Sykova, E., Agnati, L.F., Fuxe K.(2000) Long distance signalling in volume transmission. Focus on clearance mechanisms. Prog. Brain. Res. 125: 399-413.

Prokopova-Kubinova, S., and Sykova, E. (2000) Extracellular diffusion parameters in spinal cord and filum terminale of the frog. J. Neurosci. Res. 62: 530-538. Abstract . PDF file (406 k) 

2001

Chvatal, A., Anderova, M., Ziak, D., Orkand, R.K., Sykova, E. (2001) Membrane currents and morphological properties of neurons and glial cells in the spinal cord and filum terminale of the frog. Neurosci. Res. 40: 23-35. Abstract . PDF file (760 k)

Vargova, L., Chvatal, A., Anderova, M., Kubinova, S., Ziak, D., Sykova, E. (2001) Effect of osmotic stress on potassium accumulation around glial cells and extracellular space volume in rat spinal cord slices. J. Neurosci. Res. 65: 129-138. Abstract . PDF file (200 k)

Anderova, M., Kubinova, S., Mazel, T., Chvatal, A., Eliasson, C., Pekny, M., Sykova, E. (2001) Effect of elevated K+, hypotonic stress and cortical spreading depression on astrocyte swelling in GFAP-deficient mouse. Glia 35:189-203. Abstract . PDF file (400 k)

Vargova, L., Jendelova, P., Chvatal, A., Sykova, E. (2001) Glutamate-, NMDA- and AMPA-induced changes in extracellular space volume and tortuosity in the rat spinal cord. J. Cereb. Blood Flow Metab. 21: 1077-1089. Abstract . PDF file (5.7 M)

Sykova, E. (2001) Glial diffusion barriers during aging and pathological states. Prog. Brain. Res. 132: 339-363. PDF file (5.8 M)

Dezortova M, Hajek M, Tintera J, Hejcmanova L, Sykova E. (2001) MR in phenylketonuria-related brain lesions. Acta Radiol. 42: 459-466. Abstract . PDF file (2 M)

Sykova, E., Fiala, J., Antonova, T., Vorisek, I. (2001) Extracellular space volume changes and diffusion barriers in rats with kaolin-induced and inherited hydrocephalus. Eur. J. Pediatr. Surg. 11: S34-S37. PDF file (1 M) 

2002

Sykova, E., Mazel, T., Hasenohrl, R.U., Harvey, A.R., Simonova, Z., Mulders, W.H.A.M., Huston J.P. (2002) Learning deficits in aged rats related to decrease in extracellular volume and loss of difussion anisotropy in hippocampus. Hippocampus. 12: 469-479. Abstract . PDF file (2.9 M)

Lesny, P., De Croos, J., Pradny, M., Vacik, J., Michalek, J., Sykova, E. (2002) Polymer hydrogels usable for nervous tissue repair. J. Chem. Neuroanatom. 23: 243-247. Abstract . PDF file (250 k)

Kume-Kick, J., Mazel, T., Vorisek, I., Hrabetova, S., Tao, L., Nicholson, C. (2002) Independence of extracellular tortuosity and volume fraction during osmotic challenge in rat neocortex. J. Physiol. 542: 515-527. Abstract . PDF file (325 k)

Reum, T., Olshausen, F., Mazel, T., Vorisek, I., Morgenstern, R., Sykova, E. (2002) Diffusion parameters in the striatum of rats with 6-hydroxydopamine-induced lesions and with fetal mesencephalic grafts. J. Neurosci. Res. 70: 680-693. Abstract . PDF file (1.5 M)

Vorisek I., Hajek M., Tintera J., Nicolay K., Sykova E. (2002) Water ADC, extracellular space volume and tortuosity in the rat cortex after traumatic injury. Magnet. Reson. Med. 48:994-1003. Abstract

Mazel, T., Richter, F., Vargova, L., Sykova, E. (2002) Changes in extracellular space volume and geometry induced by cortical spreading depression in immature and adult rats. Physiol. Res. 51 (Suppl 1): S85-S93. Abstract . PDF file (613 k)

Liscak, R., Vladyka, V., Novotny Jr., J., Brozek, G., Namestkova, K., Mares, V., Hajek, M., Herynek, V., Sykova, E. (2002) Radiosurgical lesion of the rat hippocampus using the Leksell gamma knife: relation between radiation dose and functional and structural damage. J. Neurosurg. 97: 666-673. Abstract . PDF file (384 k) 

2003

will be added soon...

2004

will be added soon...