A postgraduate research training position, funded by the Marie Curie Training Site Project of the 5th Framework Program of the European Union, is immediately available for a period from 3 months to 1 academic year. The training program, intended as part of the applicant’s PhD. studies, will focus on one of the following projects:
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analysis of the structure of brain extracellular space and its changes during experimental models of pathological neurological states, such as ischemia, stroke, tumors, Alzheimer’s disease, hydrocephalus, traumatic brain, spinal cord injury, and others using immunohistochemical analysis, ion-selective microelectrodes and optical imaging; |
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diffusion studies in the central nervous system employing the real-time iontophoretic method of diffusion analysis; |
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electrophysiological investigations of the membrane properties of glial cells using the whole-cell patch-clamp technique; |
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studies of spinal cord injury and regeneration using implantation of hydrogels and cell therapy. |
The Institute of Neuroscience is one of the leading European centres to study ionic and volume changes in neuronal microenvironment, diffusion studies and properties of glial cells. It is equipped with state-of-the-art technology for performing ionic measurements with ion-selective microelectrodes, iontophoretic diffusion analysis both in vivo and in vitro, intrinsic optical imaging, patch-clamp studies, and other contemporary techniques of neuroscience research. Financial support of 1300 euro/month will be provided for the successful applicant’s living and travel expenses throughout his or her stay in Prague, as well as for the necessary expenditures of the research training itself. Excellent opportunities for collaborations are available both within the Institute, the clinical facilities at Motol Hospital Prague and Institute of Experimental Medicine, Academy of Sciences. Applicants must be working towards their PhD. and should have a commensurate knowledge of neuroscience. Specific experience with electrophysiological measurements, animal handling and surgery, optical imaging, brain histological techniques (e.g. confocal and electron microscopy), regeneration of the brain after focal lesions including stem cell therapy, and any type of diffusion analysis, including magnetic resonance imaging, will be helpful.
Interested individuals should contact:
Prof. Eva Syková, M.D., Ph.D., D.Sc.
Chairman
Institute of Neuroscience
Charles University, 2nd Medical Faculty
V úvalu 84,
15006 Prague 5
Czech Republic
Telephone: (+4202) 475 2204
Fax: (+4202) 475 2783
E-mail: sykova@biomed.cas.cz